Browsing Bergen Open Research Archive by Author "Lehtimäki, Lauri"

Now showing items 1-5 of 5

    • Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both 

      Pfeffer, Paul E.; Ali, Nasloon; Murray, Ruth; Ulrik, Charlotte; Tran, Trung N.; Maspero, Jorge; Peters, Matthew; Christoff, George C.; Sadatsafavi, Mohsen; Torres-Duque, Carlos A.; Altraja, Alan; Lehtimäki, Lauri; Papadopoulos, Nikolaos G.; Salvi, Sundeep; Costello, Richard W.; Cushen, Breda; Heffler, Enrico; Iwanaga, Takashi; Al-Ahmad, Mona; Larenas-Linnemann, Désirée; Kuna, Piotr; Fonseca, João A; Al-Lehebi, Riyad; Rhee, Chin Kook; Perez-de-Llano, Luis; Perng Steve, Diahn-Warng; Mahboub, Bassam; Wang, Eileen; Goh, Celine; Lyu, Juntao; Newell, Anthony; Alacqua, Marianna; Belevskiy, Andrey S.; Bhutani, Mohit; Bjermer, Leif Hilding; Bjornsdottir, Unnur; Bourdin, Arnaud; Bulow, Anna von; Busby, John; Canonica, Giorgio Walter; Cosio, Borja G.; Dorscheid, Delbert R.; Muñoz-Esquerre, Mariana; FitzGerald, J. Mark; Gil, Esther Garcia; Gibson, Peter G.; Heaney, Liam G.; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Jackson, David J.; Koh, Mariko Siyue; Ko, Hsin-Kuo Bruce; Lee, Jae Ha; Lehmann, Sverre; Chaves Loureiro, Cláudia; Lúðvíksdóttir, Dóra; Menzies-Gow, Andrew N.; Mitchell, Patrick; Papaioannou, Andriana I.; Popov, Todor A.; Porsbjerg, Celeste M.; Salameh, Laila; Sirena, Concetta; Taillé, Camille; Taube, Christian; Tohda, Yuji; Wechsler, Michael E.; Price, David B. (Journal article; Peer reviewed, 2023)
      Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients ...

    • Eosinophilic airway diseases: basic science, clinical manifestations and future challenges 

      Janson, Christer; Bjermer, Leif; Lehtimäki, Lauri; Kankaanranta, Hannu; Karjalainen, Jussi; Altraja, Alan; Yasinska, Valentyna; Aarli, Bernt Bøgvald; Rådinger, Madeleine; Hellgren, Johan; Lofdahl, Magnus; Howarth, Peter H; Porsbjerg, Celeste (Journal article; Peer reviewed, 2022)
      Eosinophils have a broad range of functions, both homeostatic and pathological, mediated through an array of cell surface receptors and specific secretory granules that promote interactions with their microenvironment. ...

    • Impact of Inititing Biologics in Patients With Severe Asthma on Long-term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry 

      Chen, Wenjia; Tran, Trung N.; Sadatsafavi, Mohsen; Murray, Ruth; Wong, Nigel Chong Boon; Ali, Nasloon; Ariti, Con; Bulathsinhala, Lakmini; Gil, Esther Garcia; FitzGerald, J. Mark; Alacqua, Marianna; Al-Ahmad, Mona; Altraja, Alan; Al-Lehebi, Riyad; Bhutani, Mohit; Bjermer, Leif Hilding; Bjerrum, Anne-Sofie; Bourdin, Arnaud; von Bülow, Anna; Busby, John; Canonica, Giorgio Walter; Carter, Victoria; Christoff, George C.; Cosio, Borja G.; Costello, Richard W.; Fonseca, João A.; Gibson, Peter G.; Yoo, Kwang-Ha; Heaney, Liam G.; Heffler, Enrico; Hew, Mark; Hilberg, Ole; Hoyte, Flavia; Iwanaga, Takashi; Jackson, David J.; Jones, Rupert C.; Koh, Mariko Siyue; Kuna, Piotr; Larenas-Linnemann, Désirée; Lehmann, Sverre; Lehtimäki, Lauri; Lyu, Juntao; Mahboub, Bassam; Maspero, Jorge; Menzies-Gow, Andrew N.; Newell, Anthony; Sirena, Concetta; Papadopoulos, Nikolaos G.; Papaioannou, Andriana I.; Perez-de-Llano, Luis; Perng (Steve), Diahn-Warng; Peters, Matthew; Pfeffer, Paul E.; Porsbjerg, Celeste M.; Popov, Todor A.; Rhee, Chin Kook; Salvi, Sundeep; Taillé, Camille; Taube, Christian; Torres-Duque, Carlos A.; Ulrik, Charlotte; Ra, Seung-Won; Wang, Eileen; Wechsler, Michael E.; Price, David B. (Journal article; Peer reviewed, 2023)
      Background Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. Objective To examine ...

    • Multidisciplinary approaches to identifying and managing global airways disease: Expert recommendations based on qualitative discussions 

      Backer, Vibeke; Cardell, Lars Olaf; Lehtimäki, Lauri; Toppila-Salmi, Sanna K.; Bjermer, Leif; Reitsma, Sietze; Hellings, Peter Wim; Weinfeld, Dan; Aanæs, Kasper; Ulrik, Charlotte Suppli; Braunstahl, Gert-Jan; Aarli, Bernt Bøgvald; Danielsen, Arild; Kankaanranta, Hannu; Steinsvåg, Sverre Karmhus; Bachert, Claus (Journal article; Peer reviewed, 2023)
      Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often ...

    • Severe asthma trajectories in adults: findings from the NORDSTAR cohort 

      von Bülow, Anna; Hansen, Susanne; Sandin, Patrik; Ernstsson, Olivia; Janson, Christer; Lehtimäki, Lauri; Kankaanranta, Hannu; Ulrik, Charlotte; Aarli, Bernt Bøgvald; Geale, Kirk; Tang, Sheila Tuyet; Wolf, Maija; Backer, Vibeke; Hilberg, Ole; Altraja, Alan; Backman, Helena; Ludviksdottir, Dora; Björnsdottir, Unnur Steina; Kauppi, Paula; Sandström, Thomas; Sverrild, Asger; Yasinska, Valentyna; Kilpeläinen, Maritta; Dahlen, Barbro; Viinanen, Arja; Bjermer, Leif; Bossios, Apostolos; Porsbjerg, Celeste (Journal article; Peer reviewed, 2023)
      Background There is limited evidence on the pathways leading to severe asthma and we are presently unable to effectively predict the progression of the disease. We aimed to describe the longitudinal trajectories leading ...